Wolves HAND Reports Genetic Expression Changes After Stem Cell Treatment in Dogs

TOKYO, Jul 23 (Pulse News Wire) – Wolves Hand CO.,LTD. (194A.T) reported significant genetic expression changes in dogs treated with stem cell-derived anti-aging solutions.

In a follow-up to their previous announcement on April 9, 2026, the company analyzed blood samples from five dogs before and after treatment with stem cell-conditioned medium (SC-CM). The study revealed a consistent reduction in TNF gene expression post-treatment across all five cases, suggesting potential anti-inflammatory effects linked to the SC-CM therapy. This finding builds upon earlier research presented at the 68th Comparative Integrative Medicine Conference in November 2025, which demonstrated increased activity levels in elderly dogs treated with SC-CM, earning the company an honorary president's award.

The latest results indicate a deeper understanding of the mechanism behind SC-CM’s anti-aging benefits. Looking ahead, Wolves Hand plans to expand its research protocols to include broader genetic analysis of blood cells, aiming to deepen academic studies on anti-aging treatments. The company also intends to contribute to the development of unified guidelines for regenerative medicine in veterinary care through ongoing clinical data accumulation.